Personally I prefer The Bat!
Can be found at
www.ritlabs.com. It have about 15 awards, and this keyfeatures:
» Support for an unlimited number of accounts and users
»Fully customizable message templates that save hours of typing
» Powerful filtering for automated message handling
»Support for S/MIME and PGP versions from 2.6x through 6.5
» Mail Dispatcher for managing email on remote servers
» Simultaneous mail processing in the background for all accounts
» Familiar Explorer-style folders for organizing messages
» Easily configurable user interface with message preview option
» Built-in HTML email viewer and message editor with spell-as-you-go
» Sophisticated address book for storing all personal information
» Unique Mail Ticker™ for email notification
» Multi-lingual interface supporting 15 languages on the fly
» Import message bases from all major email clients
» Many more features for managing email quickly and easily...
There ya go!