I figured it out!
So it happened again, but after I started using standby to conserve power.
So I was looking for an answer in the ASUS forums (which are crap to search in) and found a similar solution but it was when the computer would resume from standby.
The solution was to unplug the power cord, wait a min and plug it back in. I tried it and VIOLA! That would explain why it worked when I brought the computer in my room!
So it looks like it is a computer issue. Now I thought, BIOS issue? So I checked and there is an updated BIOS available and:
Crosshair BIOS release version 1103.
1. Fix System fails to detect Optional fan 4# and 5#.
2. Fix system might not get booted with AMD Semprom 2800+ CPU.
3. Hidden virtualization Technilogy option when installed CPU does not support this feature.
4. Fix it might fail to run certain AMD utilities under Microsoft Windows Vista OS with AMD AM2+ CPU installed.
5. Fix system might fail to overclock when using AMD AM2+ CPU.
6. Enhance compatibility with certain add-on RAID card.
7. Fix LAN might fail to work after system resumes from S3 mode.
8. Fix system might fail to resume from S3 mode when using AMD triple-core CPU.
I still don't know what caused the issue in the first place as the computer has been running with the same config for about 6 months and I've never used standby before a few days ago.
I MAY have been possible that I updated the BIOS recently, I can't remember, the version I was running was dated March 17th 2008 but the computer was running without issue since then, the new BIOS is dated March 19th 2008
Aw well hopefully this will stick.