This problem happends randomly, theres nothing wrong with the mouse ... Tryied serveral mices, both Ps/2 and USB ... The one im using is at the moment is a Mouseman Wheel / USB. ( Tried latest mouse ware - No diffrence ) It seems like WinXP are looking for something when this problem appears ... Like scanning the USB ports ??? I donno - There are no disc activity, only this annoying mouse lag. Well .. I reinstalled WinXP from scratch but the problem is still there ! I have the newest BIOS on my card (19/03/02) .... My setup is: Asus A7V kt133-C AMD athlon 1.1ghz 2x IBM deskstar disks Soundblaster 128 PCI 256 SDRAM, pc133 D-link Network card please .. Help me out ! ... This shit is driving me crazy !