Ok, this is driving me nuts, two weeks ago, I got a spanking new Logitech Cordless Navigator Duo SE mouse/KB combo. I install the I-touch and mouseware software and all works well. a week later I get a virus that forces me to wipe out my system and start over, the mouse and keyboard now work as default devices and then as soon as I install the I-touch software....bang...nothing works, the keyboard and mouse do not respond!! I end up having to plug in a old ps2 keyboard I have, boot into safe mode and uninstall the logitech i-touch software in order to get my pc to respond!!! Driving me nuts, I really want to get all the quick touch and volume controls of the keyboard working! Why did it work in my previous install, but not now! I even went to the logitech site and downloaded the latest set of mouseware and I-touch in case there were any updates? Any idea what might cause this?