Be carefull with any or these tools...many of them find "useless" values that are actually purposefull.
often times yu will remove an entry, a month or so later, something isn't working the way it's supposed to, and you won't even assoicate the two events, though they are cause and affect
for instance, in the beginning, some of these regcleaners corupted restore.
so months later, when a restore couldn't be aquired, it was hard to figure out why the files were corrupt
things like this
try not to use the bulk removal, just do the search, then make individual decisions as to what stays and goes
now this is harder then it sounds, since some of these are going to find like 400 "useless" entries
just be carefull