not Asus
I realize Asus wins many awards, but I was pretty unsatisfied. I had the A7V, a product that won many awards, but also had many problems. There is an entire website dedicated to its "quirks and issues"
www.a7vtroubleshooting.com. The USB ports are nearly unusuable, I had to purchase a PCI USB host controller, it didn't like my ATI Radeon or my Sound Blaster Live (granted, most boards with the SBlive and VIA 686B southbridge weren't happy, but eventually I either had to get a new soundcard or get a new motherboard). The onboard ATA/100 promise controller was the slowest booting component I've ever seen.
Now I have a new Soyo Dragon+, much, much nicer board. Everything works, its much more customizable, and no problems.
An ABIT was my runner up, but I forget which one. Everyone has good things to say about Asus, but I hear horror stories like mine. Everyone has good things to say about Abit, but without the horror stories.
EDIT: I forgot to mention the BIOS madness. In the 18 months I had the A7V, I went through like 5 BIOS updates. 3 were standard bug fixes, but 2 CREATED bugs and had to be replaced. So you'd upgrade to fix a bug (USB), the find out the new BIOS caused more problems, so you'd have to revert to the old BIOS, as Asus was aware of the problem with the buggy new BIOS they put out, but it takes months for them to fix it. 2 out 5 = 40%. That's not a very good failure rate.