Just ran into this, as it was the first time I came across it and thought it was rather odd/interesting I would post incase others experience it. No matter what pages a user would go to, the site itself would go and refresh every 5 seconds without fail. This happened for all 10 of the test pages I went to on his PC, each and everytime. Resetting his web settings, windows updates, emptying Internet Cache provided no help. I decided to run a Hijackthis scan just to take a peek and noticed something odd - His proxy server was actually pointing back to the local host. I went to look at it under Internet Options, and found this - Since it was checked and greyed out, I removed it using HJT, rebooted and all was well again. IE was no longer automatically refreshing pages at repeated 5 second intervals. Believe it or not, the user has dealt with this issue ever since he got his PC in April of last year.